# SiNON > Nano sciences ## Posts - [Successful Pre-Seed Raise - Copy](https://futurestartup.com/2023/11/23/a-guide-to-seed-fundraising/):   $800K (Self Funding, Friends and Family) - [Successful Pre-Seed Raise](https://futurestartup.com/2023/11/23/a-guide-to-seed-fundraising/):   $800K (Self Funding, Friends and Family) - [Partnership with the Duke Brain Tumour Center](https://www.linkedin.com/posts/afreenallam_entrepreneurship-is-a-roller-coaster-and-activity-7161072310777491457-Pquh?utm_source=share&utm_medium=member_desktop): Animal Trials conducted at Duke with applications for grants by NIH/NCI - [Termeer Fellows Program](https://www.linkedin.com/posts/afreenallam_leadership-stem-termeerfoundation-activity-7234980550321606657-iBvP?utm_source=share&utm_medium=member_desktop): Provides value-driven leadership programming and supports to first time CEOs of early stage biotech /life science organizations - [Graduate from CDL Neuro Toronto](https://www.linkedin.com/posts/cdl-toronto_neuro-buildsomethingmassive-activity-7204559101874372608-t0e_?utm_source=share&utm_medium=member_desktop): Over 3000 applicants.  Only 20 Neuro companies selected and 8 graduated from the program.  - [Mass Challenge Graduate](https://www.linkedin.com/school/masschallenge/people/): Global, Zero-equity start-up accelerator founded in Boston, MA in 2009 - [SiNON Nano Sciences Shines at BIO Start-Up Stadium 2024 with Seed-Stage Victory](https://bio.news/bio-convention/bio-2024-start-up-stadium-sinon-nano-sciences-seed-stage-winner/) - [Life Science Nation published an article on "The Key to SiNON Nano Sciences’ Success in the RESI South Innovator’s Pitch Challenge."](https://blog.lifesciencenation.com/2024/05/09/the-key-to-sinon-nano-sciences-success-in-the-resi-south-innovators-pitch-challenge/) - [Issuu featured Afreen Allam on the cover of 'Durham Magazine, May 2019'](https://issuu.com/shannonmedia/docs/dmm19/36) - [Forbes NEXT 1000](https://www.linkedin.com/posts/afreenallam_thenext1000-forbes-forbeswomen-activity-6767458901777555456-NrNm):   Nominations screened by top business minds for a list of 1000 new faces who are redefining what it means to build and run a  business today.   - [NC IDEA Grant Recipient $50,000 Grant](https://amp.heraldsun.com/news/business/article151253082.html):   Grants applied to innovative companies with proprietary IP and sustained competitive advantage that are solving large problems. - [Duke Start-up Challenge Winner $50,000 Grant](https://researchblog.duke.edu/2015/10/06/sinon-overcomes-barriers-to-win-grand-prize/):   SiNON is honored to win the Grand Prize at Duke University’s 16th Annual Start-Up Challenge. Over 250 companies applied and SiNON Win the Grand Prize .  - [Afreen Allam, the Founder and CEO of SiNON Nano Sciences, was recognized by the Bio International Convention for her groundbreaking contributions to the field of nanomedicine.](https://convention.bio.org/speakers/afreen-allam):     - [Wral Tech Wire highlights Sister Power: Introducing 33-year-old Afreen Allam – a Muslim woman, CEO, and inventor of ‘Carbon Dot’](https://wraltechwire.com/2022/02/11/sister-power-meet-33-year-old-afreen-allam-a-woman-a-muslim-a-ceo-and-inventor-of-carbon-dot/) - [The Rotman School of Management, part of the University of Toronto published about developing Carbon Nano Particles](https://creativedestructionlab.com/companies/sinon-nano-sciences/):   - [Afreen Allam delivered a lightning round pitches at the CED Life Science Conference.](https://www.youtube.com/watch?v=Q2MtrJq1qJE&t=5s) - [SiNON Nano Sciences Joins Prestigious Termeer Fellowship for Life Sciences Leadership](https://www.linkedin.com/posts/the-termeer-foundation_leadership-stem-termeerfoundation-activity-7234537808957243392--Jnc):     ## Pages - [Technology Focus](https://sinontx.com/technology-focus/): Innovative Therapeutic Solutions for Brain Cancer and Metastases Initial Focus: Tackling Glioblastoma Challenges Glioblastoma (GBM) is a highly aggressive and lethal brain cancer, notorious for its rapid growth, high recurrence, and significant resistance to conventional therapies. Approximately 80,000 new primary brain tumor cases are diagnosed annually in the U.S., with GBM accounting for about 15% and carrying a morbidity rate exceeding 70%. The Blood-Brain Barrier (BBB) Challenge: Treating brain cancers like GBM is hindered by the BBB, which blocks drug entry to the brain. Only a small fraction of therapies can cross: under 2% of small-molecule drugs, less than 5% […] - [My account](https://sinontx.com/my-account/) - [Checkout](https://sinontx.com/checkout/) - [Cart](https://sinontx.com/cart/) - [Shop](https://sinontx.com/shop/) - [Technology Partners](https://sinontx.com/technology-partners/): Strategic Partnerships for Advanced Drug Delivery Solutions We work closely with our pharmaceutical/academic partners to unlock new possibilities for drug delivery and therapeutic impact. Our patented Carbon Nanoparticle (CNP) technology offers a adaptive platform for encapsulating and delivering therapeutic agents, allowing us to overcome critical barriers, such as crossing the blood-brain barrier (BBB) and reducing toxicity. Our partnership process is designed to ensure the seamless integration of our technology with your therapeutic goals. From initial screening to clinical readiness, we support each stage of development with scientific rigor and attention to scalability: Our Partnership Process Initial Screen: We begin with […] - [Home](https://sinontx.com/): Empowering Targeted Therapeutics with Carbon Nanoparticles for Sustained Release, Reduced Toxicity and Enhanced Bioavailability. Transforming Neurological Therapies with SiNON’s Carbon Nanotechnology We are committed to advancing therapies for severe neurological conditions.  Our Carbon Nanoparticle (CNP) technology enables targeted drug delivery across the Blood-Brain Barrier (BBB), with high specificity and controlled, sustained release.  This approach maximizes drug concentration in the brain, offering key advantages: Reduced Dosage: Smaller drug quantities reduce toxicity and side effects, enhancing patient safety. Improved Outcomes:  Targeted, sustained release boosts therapeutic effectiveness. Cost-Efficiency: Controlled delivery lowers treatment costs, benefiting both healthcare providers and patients. Built on scientific rigor, […] - [About Us](https://sinontx.com/aboutus/): Transforming Therapeutics with Carbon Nanotechnology SiNON Nano Sciences an early-stage nanotechnology company developing non-toxic carbon nanoparticle formulations to enhance drug efficacy and reduce toxicity At SiNON Nano Sciences, we are advancing therapeutic innovation with our patented carbon nanoparticle technology. This platform transforms drug delivery by boosting bioavailability, extending half-life, and lowering toxicity through targeted delivery. Our nanoparticles effectively cross the Blood-Brain Barrier, tackling critical challenges that have restricted the success of certain therapies in clinical trials. Additionally, our technology can extend the lifecycle of near-expiration drugs, revitalizing them with optimized formulations and broader therapeutic applications. Our mission is to leverage this […] - [News](https://sinontx.com/news/): Media News Recognition SiNON Nano Sciences Shines at BIO Start-Up Stadium 2024 with Seed-Stage Victory Life Science Nation published an article on “The Key to SiNON Nano Sciences’ Success in the RESI South Innovator’s Pitch Challenge.” Issuu featured Afreen Allam on the cover of ‘Durham Magazine, May 2019’ Wral Tech Wire highlights Sister Power: Introducing 33-year-old Afreen Allam – a Muslim woman, CEO, and inventor of ‘Carbon Dot’ Afreen Allam, the Founder and CEO of SiNON Nano Sciences, was recognized by the Bio International Convention for her groundbreaking contributions to the field of nanomedicine. The Rotman School of Management, part […] - [Patents](https://sinontx.com/patents-2/): SiNON Nano Sciences Patents SiNON Nano Sciences is proud to hold awarded patents in United States and India, with a patent pending in the EU, underscoring our commitment to innovation and excellence in advanced drug delivery systems.  These patents recognize our proprietary technologies and methodologies, positioning us as leaders in oncology and therapeutic development.  Our Global Patent Achievements US Patent Awarded Water soluble fluorescent quantum carbon dots. Patent Number: US 20110217721A1 Filling Date: March 8, 2010 Granted Date: January 22, 2013 View the Full Patent: Click Here Nano Particle Compositions and methods of making and using the same Patent Number: […] - [CNP Feature](https://sinontx.com/carbon-nano-particle-feature/): Carbon Nano Particles SiNON Nano Sciences leverages the advanced features of Carbon Nano Particles to pioneer innovative solutions in the field of therapeutics. By integrating the unique properties of Raman Spectra, FTIR imaging, DLS size distribution, solubility, and fluorescence capability, we ensure the development of cutting-edge therapeutic and diagnostic applications that are both effective and reliable. Our commitment to harnessing the potential of CNPs underscores our dedication to advancing healthcare and improving patient outcomes Multiple Applications A platform technology with diverse applications CNP Therapeutics Targeted Drug Delivery Controlled-release Cross the Blood Brain Barrier Fluorescent Bio-Imaging & Sensing Non-invasively Self-fluorescing Diagnostic […] - [Technology](https://sinontx.com/technology/): Technology SiNON Nano Sciences are pioneering the development of a novel, effective, and targeted delivery system for administering therapeutics through oral, intravenous and other desirable routes.  Our approach aims to enhance bioavailability while ensuring a slow and sustained release, maintaining the optimal concentration of therapeutics at the site of action.  This cutting-edge delivery system is designed to improve therapeutic outcomes and patient experiences.  Enhanced Bioavailability: Maximizing the absorption of therapeutics through precise delivery mechanisms. Sustained Release: Ensuring prolonged therapeutic effects with controlled release for consistent efficacy.  Initial Focus Area GLIOBLASTOMA Glioblastoma is an aggressive type of cancer that occurs in the […] - [Contact Us](https://sinontx.com/contactus/): Contact Us Contact Form Demo NameEmailYour MessageSubmit Address SiNON Nano Sciences, 321 Olive Branch Road Durham NC 27703 Email info@sinontx.com - [Leadership](https://sinontx.com/leadership/): Diverse Team Our team, with expertise in scientific research areas like nano chemistry, radiation oncology and  degrees in fields such as medicine,  neuroscience, biochemistry, microbiology, engineering and business the SiNON Nano Sciences team is ready to tackle challenges.  Our small size makes us quick, responsive and our experience ensures we can execute and exceed expectations. Leadership Advisors Our Leadership Team Our Leadership team integrates advanced medical innovations and cutting-edge nanosciences to revolutionize patient care.  Their expertise drives pioneering breakthroughs that enhance healthcare outcomes and well-being. With a vision for the future, they are committed to shaping the next generation of […] - [Assets](https://sinontx.com/assets/): Assets SiNON Nano Sciences assets are based on cutting-edge Carbon Nano Particles(CNP) technology, which forms the basis of our innovative products aimed at improving drug delivery systems and therapeutic outcomes. Versatility: Our CNPs are engineered to conjugate with various compounds, enhancing their functionality and application across different therapeutic areas. Targeted Delivery: By conjugating CNPs with molecules like Arginine Peptide, we can achieve precise targeting, reducing side effects and increasing treatment efficacy.Enhanced Drug Encapsulation: Our CNP-based formulations are designed to encapsulate drug, improving their stability and controlled release. CNP Asset Name: CNP Asset Description: Carbon Nano Particle Code: CNP-1001… View More CNP-Arg […] ## Products - [FESEM](https://sinontx.com/product/fesem/): A FESEM (Field Emission Scanning Electron Microscope) image of CNPs (Carbon Nanoparticles) provides a highly detailed view of the structure, morphology, and surface characteristics of these particles at the nanoscale. - [EDX](https://sinontx.com/product/edx/): EDX (Energy Dispersive X-ray Spectroscopy) is a powerful analytical technique often used in conjunction with Scanning Electron Microscopy (SEM), including Field Emission Scanning Electron Microscopy (FESEM), to characterize the elemental composition of materials such as  (CNPs). - [DLS of CNP - Arginine](https://sinontx.com/product/dls-of-cnp-arginine/):
The image shows an infrared (IR) spectrum obtained via Attenuated Total Reflectance (ATR) spectroscopy, displaying two distinct plots in red and blue, representing different samples or conditions of CNP (possibly Cationic Nanoparticles) and Arginine.
- [DLS of CNP](https://sinontx.com/product/atr-ir-attenuated-total-reflectance-infrared-spectroscopy-of-cnp-arginine-copy/):
The image shows an infrared (IR) spectrum obtained via Attenuated Total Reflectance (ATR) spectroscopy, displaying two distinct plots in red and blue, representing different samples or conditions of CNP (possibly Cationic Nanoparticles) and Arginine.
 
- [ATR-IR of CNP-Arginine](https://sinontx.com/product/atr-ir-cnp-arginine/):
The image shows an infrared (IR) spectrum obtained via Attenuated Total Reflectance (ATR) spectroscopy, displaying two distinct plots in red and blue, representing different samples or conditions of CNP (possibly Cationic Nanoparticles) and Arginine.  
- [ATR-IR of CNP](https://sinontx.com/product/atr-ir-of-cnp/): The image represents an ATR-IR (Attenuated Total Reflectance Infrared Spectroscopy) spectrum of Carbon Nanoparticles (CNP). - [CNP - Raman Spectra](https://sinontx.com/product/cnp-raman-spectra/):
The image shown a Raman spectrum for a material, showing two prominent peaks.
- [CNP UV-Vis Absorption Spectra](https://sinontx.com/product/cnp-uv-vis-absorption-spectra/): The image shows an absorption spectrum for a lyophilized sample of carbon nanoparticles (CNP). - [Zeta potential (mV) of CNP Arginine](https://sinontx.com/product/zeta-potential-mv-of-cnp-arginine/): The Zeta potential of -33 mV for carbon nanoparticles functionalized with Arginine highlights their stability and surface charge in suspension. The negative charge ensures electrostatic repulsion between particles, preventing aggregation and maintaining a stable colloidal solution. This property is essential for enhancing the effectiveness of the nanoparticles in drug delivery and other therapeutic applications. Zeta potential indicates particle stability and charge distribution A negative value of -33 mV suggests strong repulsion between particles. Functionalization with Arginine enhances biocompatibility and application in drug delivery systems. - [Zeta potential (mV) of CNP](https://sinontx.com/product/zeta-potential-mv-of-cnp/): Zeta potential is a key measure of nanoparticle stability and surface charge in suspension, expressed in millivolts (mV). A value of -41.09 mV indicates a highly negative charge, promoting strong electrostatic repulsion between particles. This prevents agglomeration and ensures the stability of the colloidal solution, making it ideal for applications such as drug delivery, where stability is crucial for effectiveness.   - [CNP-Arg-TMZ](https://sinontx.com/product/cnp-arg-tmz/): Asset Name: CNP-Arg-TMZ Asset Description: Temazolomide encapsulated in Carbon Nano Particle conjugated with Arginine Code: CNPArgTMZ-2004 Click to view additional asset details and features - [CNP-Arg-TPT](https://sinontx.com/product/cnp-arg-tpt/): Asset Name: CNP-Arg-TPT Asset Description: Topotecam encapsulated in Carbon Nano Particle conjugated with Arginine Code: CNPArgTPT-2003 Click to view additional asset details and features - [CNP-Arg-PTX](https://sinontx.com/product/cnp-arg-ptx/): Asset Name: CNP-Arg-PTX Asset Description: Paclitaxel encapsulated in Carbon Nano Particle conjugated with Arginine Code: CNPArgPTX-2002 Click to view additional asset details and features - [CNP-TMZ](https://sinontx.com/product/cnp-tmz/): Asset Name: CNP-TMZ Asset Description: Temazolomide encapsulated in Carbon Nano Particle Code: CNPTMZ-1003 Click to view additional asset details and features - [CNP-TPT](https://sinontx.com/product/cnp-arg-copy-2/): Asset Name: CNP-TPT Asset Description: Topotecan encapsulated in Carbon Nano Particle Code: CNPTPT-1003 Click to view additional asset details and features - [CNP-PTX](https://sinontx.com/product/cnp-ptx/): Asset Name: CNP-PTX Asset Description: Paclitaxel encapsulated in Carbon Nano Particle Code: CNPPTX-1002 Click to view additional asset details and features - [CNP-Arg](https://sinontx.com/product/cnp-arg/): Asset Name: CNP-Arg Asset Description: Carbon Nano Particle conjugated with Arginine Peptide Code: CNPArg-2001 Click to view additional asset details and features - [CNP](https://sinontx.com/product/cnp/): Asset Name: CNP Asset Description: Carbon Nano Particle Code: CNP-1001 Click to view additional asset details and features [comment]: # (Generated by Hostinger Tools Plugin)